Acute Porphyria Drug Database

C01CA14 - Dopexamine
Propably not porphyrinogenic
PNP

Rationale
Catecholamine. Non-CYP metabolism. No data pointing to CYP-interaction.
Chemical description
Catecholamine.
Therapeutic characteristics
Synthetic catecholamine used in intravenous short-duration treatment of chronic heart failure. Administered in infusion 1-6 ug/kg/minute in 0.9 %NaCl or 5% glucose solution.
Metabolism and pharmacokinetics
Metabolized in the liver via O-methylation and O-sulfatation of the catechol hydroxyl group. Half time in blood 6-7 minutes.

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