Sulfonamide type of drug. Clinical experience points, however, to non-porphyrinogenicity.

sulfonamide type of drug.

Thiazide diuretic and antihypertensive.

More specific data on metabolism are lacking. No observations of CYP interaction. Mainly eliminated via non-renal mechanisms, only 30 % excreted in unchanged form in urine.

Thunell, patient report tolerated (n=1). Andersson, patient report (n=11): tolerated.

Uneventful use reported in 37 patients with acute porphyria.