Beta-blocker, not metabolised. Occasional clinical observation of tolerance. Two references state non-porphyrinogenicity.

(To be edited, initial data ST OCT 04) Watersoluble beta-receptor blocking substance. Excreted unchanged in urine. Thunell, patient reports (n=3 ): tolerated. South African list: use. French list: authorized. EPI: safe (betablockers)

Uneventful use reported in 6 patients with acute porphyria.