D01AC03 - Econazole |
Propably not porphyrinogenic |
PNP |
Rationale
CYP-inducer. Probably insignificant systemic exposure.
Chemical description
(To be edited, initial data ST OCT 04) Broadspectrum imidazole antimycotic for dermatological use (gel/ creme/ liniment 1%). Inhibitor of CYPs 3A4 (potent), 2E1, 19 (aromatase), CYP-inducer. Probably only slight systemic absorbtion.
IPNet drug reports
Uneventful use reported in 4 patients with acute porphyria.
Similar drugs
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