D01AC10 - Bifonazole |
Propably not porphyrinogenic |
PNP |
Rationale
Inhibitor of CYPs 17 (potent), C19 (aromatase), 2E1, 11B1 and 3A4. Probably insignificant systemic exposure.
Chemical description
(To be edited, initial data ST OCT 04) Imidazole antimycotic for dermatological use (creme 1%). Inhibitor of several CYPs. Systemic absorbtion from the skin is very low; 0.6-0.8 %.
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