Acute Porphyria Drug Database

D01AC10 - Bifonazole
Propably not porphyrinogenic
PNP

Rationale
Inhibitor of CYPs 17 (potent), C19 (aromatase), 2E1, 11B1 and 3A4. Probably insignificant systemic exposure.
Chemical description
Imidazole antimycotic for dermatological use (creme 1%). Inhibitor of several CYPs. Systemic absorbtion from the skin is very low; 0.6-0.8 %.

Similar drugs
Explore alternative drugs in similar therapeutic classes D01A / D01AC or go back.

 
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