Acute Porphyria Drug Database

D01AE15 - Terbinafine
Propably not porphyrinogenic
PNP

Rationale
Terbinafine (ATC code: D01A E15) for topical application is classified as Probably not porphyrinogenic because of minimal systemic exposure. For more details of the metabolism of terbinafine please refer to the monograph of terbinafine for systemic use (ATC code: D01B A02).
Hepatic exposure
Negligible
Metabolism and pharmacokinetics
Less than 5% of the dose is absorbed after topical application and systemic effect is therefore very limited (SPC).
IPNet drug reports
Uneventful use reported in 6 patients with acute porphyria.

References

  1. Summary of Product Characteristics
  2. Norwegian medicines agency. Summary of Product Characteristics (SPC). terbinafin. #1346

Similar drugs
Explore alternative drugs in similar therapeutic classes D01A / D01AE or go back.

 
© NAPOS 2024
An unhandled error has occurred. Reload 🗙