D07AB07 - Fluprednidene |
Not porphyrinogenic |
NP |
Rationale
Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
(To be edited, initial data ST OCT 04) Moderately strong glucocorticoid used for skin treatment. Systemic exposure in application on large areas of the body. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.
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