D07AC13 - Mometasone |
Not porphyrinogenic |
NP |
Rationale
Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
(To be edited, initial data ST OCT 04) Strong glucocorticoid, creme/salve 0.1%, cutaneous solution 0.1%. Used in psoriasis and other steroide sensitive dermatoses. Risk for systemic exposure in application on large areas of the skin. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.
IPNet drug reports
Uneventful use reported in 5 patients with acute porphyria.
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