Alkaloid, probably insignificant hepatic load. Five references: safe.

(To be edited, initial data ST OCT 04) Tertiary amine alcaloide used preoperatively,and in bradycardia, hypersecretion and spastic intestinal conditions, parenterally administered 0,4-0.5 mg. South African list: use. French list: authorized. Kalman, Bonkowski: Belived to be safe. Moore MR, Hift RJ. Drugs in the acute porphyrias - toxicogenetic diseases. Cell Mol Biol 43:89, 1997: safe. Eales L. Porphyria and the dangerous life-threatening drug: safe.

Uneventful use reported in 1 patient with acute porphyria.