H02AB01 - Betamethasone |
Propably not porphyrinogenic |
PNP |
Rationale
Glucocorticoid. Several references consider it safe.
Chemical description
(To be edited, initial data ST OCT 04) Glucocorticoid used in treatment of staus asthmaticus, severe allergic conditions, anaphylaxis, etc. Mineralocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moores list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncans Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939: safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe
Therapeutic characteristics
Hepatic exposure
Metabolism and pharmacokinetics
Preclinical data
Personal communication
Published experience
IPNet drug reports
Uneventful use reported in 7 patients with acute porphyria.
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