Not metabolised. No data pointing to CYP-interaction. Conflicting references.

(To be edited, initial data ST OCT 04) Parenteral cephalosporin antibioti used (2 g x 1-2) preoperatively in colo-rectal surgery. Not significantly metabolized. No data pointing to CYP-affinity. Mainly excreted in unchanged form by the kidneys. South African list: use with caution . French list: unsafe.