Not metabolised. No data pointing to CYP interaction. Conflicting references.

(To be edited, initial data ST OCT 04) Parenteral betalactamase stable cephalosporin used in bacterial meningitis and as prophylaxis in abdominal surgery. Not metabolized. Excreted by bile and the kidneys. No data pointing to CYP-affinity. South African list: use with caution. French list: use.

Uneventful use reported in 3 patients with acute porphyria.