J01DD04 - Ceftriaxone |
Propably not porphyrinogenic |
PNP |
Rationale
Not metabolised. No data pointing to CYP interaction. Conflicting references.
Chemical description
Parenteral betalactamase stable cephalosporin used in bacterial meningitis and as prophylaxis in abdominal surgery. Not metabolized. Excreted by bile and the kidneys. No data pointing to CYP-affinity. South African list: use with caution. French list: use.
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
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