Based on the pharmacokinetics of the cholera, inactivated, whole cell vaccine, there are no conceivable porphyrinogenic effects.

Inactivated Vibrio Cholerae of different strains of serogroup O1 and the B subunit of the cholera toxin.

Dukoral is indicated for active immunisation against disease caused by Vibrio cholerae serogroup O1 in adults and children from 2 years of age who will be visiting endemic/epidemic areas. The vaccine is administered orally as two doses (three doses for children under 6), taken at least one week apart.

The cholera vaccine is not metabolized by the cytochrome P450 system.

Uneventful use reported in 1 patient with acute porphyria.