Probably insignificant systemic exposure.

(To be edited, initial data ST OCT 04) Contact laxative giving rise in the colon to free phenols that inhibit water resorbtion, administered perorally in a dose o5 5-10 mg/d. No data on systemic absorbtion. Used in Swedish porphyria wards.

Uneventful use reported in 5 patients with acute porphyria.