J07BA01 - Encephalitis, Tick Borne, Inactivated, Whole Virus |
Propably not porphyrinogenic |
PNP |
Side effects
Common adverse reactions of the oral TBE virus vaccine that can be confused with an acute porphyric attack are nausea and vomiting. These side effects may potentially be porphyrinogenic if leading to a decrease in carbohydrate intake.
Rationale
Based on the pharmacokinetics of the encephalitis, tick borne, inactivated, whole virus vaccine, there are no conceivable porphyrinogenic effects.
Chemical description
Inactivated tick-borne encephalitis virus of the strain Neudörfl.
Therapeutic characteristics
The tick borne encephalitis virus vaccine is indicated for the active (prophylactic) immunization of adults and children over the age of 1 against tick-borne encephalitis (TBE). It is administered by intramuscular injections according to a three dose schedule.
Metabolism and pharmakokinetics
The TBE virus vaccine is not metabolized by the cytochrome P450 system.
References
- Government bodies
- Norwegian Institute of Public Health. Vaksinasjonsveilederen. www.fhi.no (updated 13.10.2015). #1857
- Summary of Product Characteristics
- The electronic Medicines Compendium (emc). Summary of Product Characteristics (SPC). TicoVac. (Last edition: July 2016). #1872
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