Acute Porphyria Drug Database

M01AE14 - Dexibuprofen
Propably not porphyrinogenic
PNP

Rationale
Racemic form of ibuprofen: "Propionic acid derivative metabolised mainly by CYP 2C9. No clinical data pointing to CYP-inducing effects."
Chemical description
(To be edited, initial data ST OCT 04) Tabl 200-1200 mg/d. Analgetic and antiflogistic propionic acid derivative. Racemic form of ibuprophene. Metabolized in the liver by hydroxylation (CYP2C9 and 2C8) and carboxylation. No data pointing to CYP-induction.

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