(Preliminary text, to be edited) Substrate and in some cases inhibitor of Cyp2D6. No basis for assumption of Cyp TDI properties. 40 reports of safe use indcates that the phenothiaze -N/-S heterocycle is devod of porphyrogenicity in a way not significantly influenced by side chain structures.

Phenothiazin derivatives with dimethylaminopropyl side chain or piperazine ring side chain. Generally administered as water-soluble salts.

Neuroleptics, anxtiolytics Antimuscarinic effects. Confounding side effects: Tachycardia

In some cases probably significant

Generally metabolized by Cyp2D6, some being inhibitors of CypD6 without effects connected with significant Cyp TDI.

Uneventful use reported in 1 patient with acute porphyria. 40 reports of safe use of drugs within these two groups of phenotiazines, none of porphyrogenicity