Acute Porphyria Drug Database

A07DA03 - Loperamide
Propably not porphyrinogenic
PNP

Rationale
Synthetic opiate, some systemic absorption takes place. Probably CYP-metabolised. No data pointing to CYP-induction. Two references state non-porphyrinogenicity.
Chemical description
Synthetic opiate used in diarrhoea. Metabolized by oxidative N-demethylation. No data given on CYP-interaction, South African list: use. French list: authorized
IPNet drug reports
Uneventful use reported in 17 patients with acute porphyria.

Similar drugs
Explore alternative drugs in similar therapeutic classes A07D / A07DA or go back.

 
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