R03BB04 - Tiotropium Bromide |
Propably not porphyrinogenic |
PNP |
Rationale
Probably insignificant metabolic exposure
Chemical description
(To be edited, initial data ST OCT 04) Anticholinergic bronchodilator used in inhalation powder (18 ug/dose) in KOL. 75 % excreted in unchanged form in urine, the rest metabolized by CYPs.
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
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