Probably no significant systemic exposure. Several references: use/safe/authorised.

(To be edited, initial data ST OCT 04) Glucocorticoid in solution 1mg/mL for ophtalmic and othologic use. South African list: use French list: authorized Kalman, Bonkowski: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the porphyrias in Bondy PK, RosenbergLE (eds.): Duncan s Disease of metabolism. Philadelphia, WB Saunders,1980, p 939: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997 : safe

Uneventful use reported in 1 patient with acute porphyria.