Bromfenac is administered locally in the eye and plasma concentrations are not quantifiable. The hepatic exposure is insignificant

Benzophenone

Bromfenac is an anti-inflammatory agent used in the treatment of postoperative ocular inflammation following cataract extraction in adults. One drop is administered in the eye twice daily in two weeks after cataract extraction (SPC).

Bromfenac has not been detected in plasma after ocular administration (SPC).

In vitro studies indicate that bromfenac is metabolized by CYP2C9 (SPC).