Acute Porphyria Drug Database

B01AX05 - Fondaparinux
Propably not porphyrinogenic
PNP

Rationale
Synthetic substance. The dose is in larger parts not metabolised. No clinically significant CYP-interactions observed.
Chemical description
(To be edited, initial data ST OCT 04) Synthetic and selective inhibitor of activated factor X. Administered subcutaneously, 2.5 mg/d, for prevention agaist thromoembolic episodes in patients undergoing orthopedic surgery. Excreted in unchanged form to 64-77%. Has been shown not to inhibit the metabolism of CYP metabolized drugs.

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