Prostaglandin. Probably only insignificant hepatic exposure.

(To be edited, initial data ST OCT 04) Tablets; 0.2-0.8 mg/d. Synthetic prostaglandin, which is inhibitor of ventricular secretion. Mucosaprotective effect against ASA induced ventricular lesions. Metabolized in several organs by beta-omega oxidation. Misoprostol and misoprostolic acid is excrered by the kidneys and faeces as various metabolites. South African list: use with extreme caution only. French list: authorized

Uneventful use reported in 2 patients with acute porphyria.