C01CA01 - Etilefrine |
Propably not porphyrinogenic |
PNP |
Rationale
Non-CYP metabolism. No data pointing to CYP-interaction.
Chemical description
Structurally related to endogenous adrenaline, lacking one catechol-hydroxy moiety, and N-ethyl substituent instead of N-methy.
Therapeutic characteristics
Adrenergic substance used in hypotension.
Metabolism and pharmakokinetics
Metabolized by conjugation to sulfates and glucuronides and by deamination to hydroxymandelic acid.
Personal communication
None
Published experience
None
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