Monograph
C07AB03 - Atenolol |
Not porphyrinogenic |
NP |
Rationale
Considerable clinical experience points to non-porphyrinogenicity.
Chemical description
Hydrophilic catecholamine derivative
Therapeutic characteristics
Selective antagonist of adrenergic beta1 adrenoceptors (beta blocker) for the treatment of e.g. hypertension, angina, dysrhythmias, myocardial infarction. Adverse reactions that can mimick porphyria symptoms are fatigue/muscle weakness, depression, sleep disturbance, gastrointestinal effects (nausea and vomiting, diarrhoea, constipation and abdominal cramping).
Hepatic exposure
Significant
Metabolism and pharmacokinetics
Less than 10% of an oral dose is metabolized, the rest being excreted in unchanged form in urine. 85 to 100 % of an intravenous dose is excreted unchanged in the urine.
Preclinical data
None
Personal communication
Used in Swedish porphyria ward:
IPNet drug reports
Uneventful use reported in 75 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Scientific articles | |
| 1. | Pathologic quiz case. A 35 year old woman with a history of arrhythmia and liver failure. Arch Pathol Lab Med 2002;126(6):751-2.
Mikolaenko MD, Conner MG. |
|
| 2. | Use of sufentanil and atracurium anesthesia in a patient with acute porphyria undergoing coronary artery bypass surgery. J Cardiothorac Vasc Anesth 1995;9(1):75-8.
Sneyd JR, Kreimer-Birnbaum M et al. |
|
Tradenames
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Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
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Atenolol Accord 100 mg tabletten · Atenolol Accord 25 mg Tabletten · Atenolol Accord 50 mg tabletten · Atenolol Aurobindo 100 mg, filmomhulde tabletten · Atenolol Aurobindo 25 mg, filmomhulde tabletten · Atenolol Aurobindo 50 mg, filmomhulde tabletten · Atenolol CF 25 mg, tabletten · Atenolol CF 50 mg, tabletten · Atenolol Sandoz 100 mg, filmomhulde tabletten · Atenolol Sandoz 100, tabletten 100 mg · Atenolol Sandoz 25 mg, filmomhulde tabletten · Atenolol Sandoz 25, tabletten 25 mg · Atenolol Sandoz 50 mg, filmomhulde tabletten · Atenolol Sandoz 50, tabletten 50 mg · Atenolol Teva 100 mg, tabletten · Atenolol Teva 25 mg, tabletten · Atenolol Teva 50 mg, tabletten · Atenolol Xiromed 100 mg filmomhulde tabletten · Atenolol Xiromed 25 mg filmomhulde tabletten · Atenolol Xiromed 50 mg filmomhulde tabletten 
Atenolol EG 100 mg comp. · Atenolol EG 25 mg comp. · Atenolol EG 50 mg comp. · Atenolol Teva 100 mg comp. · Atenolol Teva 25 mg comp. · Atenolol Teva 50 mg comp. · Atenolol Viatris 100 mg compr. pellic. · Atenolol Viatris 50 mg compr. pellic. · Tenormin · Tenormin Mitis 50 50 mg comp. · TENORMIN-100 100 mg comp. 
Atenolol · ATENOLOL ALTER 100 mg COMPRIMIDOS EFG · ATENOLOL ALTER 50 mg COMPRIMIDOS EFG · ATENOLOL ARISTO 50 mg EFG · Atenolol Aurovitas 100 mg Comprimidos Recubiertos con Pelicula efg · ATENOLOL CINFA 100 mg COMPRIMIDOS EFG · Atenolol Combix 100 mg Comprimidos Recubiertos con pel?Cula efg · Atenolol Combix 50 mg Comprimidos Recubiertos con pel?Cula efg · ATENOLOL NORMON 100 mg COMPRIMIDOS RECUBIERTOS EFG · ATENOLOL NORMON 50 mg COMPRIMIDOS RECUBIERTOS EFG · ATENOLOL RATIOPHARM 100 mg COMPRIMIDOS RECUBIERTOS EFG · ATENOLOL SANDOZ 50 mg COMPRIMIDOS RECUBIERTOS CON PEL?CULA EFG · ATENOLOL TARBIS 100 mg COMPRIMIDOS EFG · ATENOLOL TARBIS 50 mg COMPRIMIDOS EFG · BLOKIUM 100 mg COMPRIMIDOS · BLOKIUM 50 mg COMPRIMIDOS · Tenormin · TENORMIN 0,5 mg/ml SOLUCION INYECTABLE 
Atenol · Atenololo · Seles Beta · Tenormin · Tensiblock 
ATENOLOL ARENA 100 mg · ATENOLOL ARENA 50 mg · ATENOLOL LPH 100 mg · ATENOLOL LPH 50 mg · ATENOLOL MEDUMAN 50mg 
Antipressan · Atenix 100 · Atenix 25 · Atenix 50 · Atenolol · Tenormin · Tenormin LS 
Atenodan · Atenolol 2care4 · Atenolol Epione Medicine · Atenolol Medartuum · Atenolol Medical Valley · Atenolol Nordic Prime · Atenolol Orifarm · Dantanol 
Atenolol 1a pharma · Atenolol aliud · Atenolol orifarm · Atenolol sandoz · Atenolol Viatris · Atenolol-ratiopharm · Tenormin 
Atenolol Sanofi 25 · Atenolol Sanofi 50 
Atenolol-eg · Tenormin · Tenormin Minor · Tenormin Mitis 
Atenolol Viatris 
Atenblock · Tenoprin 
Prinorm®
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