Monograph
C08DB01 - Diltiazem |
Probably porphyrinogenic |
PRP |
Rationale
Substrate for several CYPs, including 3A4. Potent mechanism-based CYP 3A4 inhibitor.
Chemical description
Benzodiazepine dervative with calcium antagonistic action, metabolized to desmetyl and desacetyl diltiazem. Substrate of CYPs 2C8,2C9, 2D6, 3A4, 3A5, 3A7. Inhibitor of 2C8, 2C9, 2D6. Potent mechanism-based inhibitor of 3A4. Andersson, patient report (n=3): tolerated. James and Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use with care. South African list: use with care. French list: authorized. Kauppinen and Mustajoki. Prognosis of acute porphyria: Occurrence of acute attacks, precipitating factors,and assocciated diseases. Medicine 1992; 71, 1-13 : tolerated (n=1).
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
Diltiazem HCl Auro retard 120 mg, tabletten met gereguleerde afgifte · Diltiazem HCl Auro retard 90 mg, tabletten met gereguleerde afgifte · Diltiazem HCl Aurobindo 60 mg, tabletten · Diltiazem HCl retard 200 mg Teva, capsules met gereguleerde afgifte · Diltiazem HCl retard 300 mg Teva, capsules met gereguleerde afgifte · Diltiazem HCl Retard Mylan 120 mg, capsules met gereguleerde afgifte · Diltiazem HCl Retard Mylan 180 mg, capsules met gereguleerde afgifte · Diltiazem HCl Retard Mylan 200 mg, capsules met gereguleerde afgifte · Diltiazem HCl Retard Mylan 240 mg, capsules met gereguleerde afgifte · Diltiazem HCl Retard Mylan 300 mg, capsules met gereguleerde afgifte · Diltiazem HCl Retard Mylan 360 mg, capsules met gereguleerde afgifte · Diltiazem HCl Sandoz retard 200 mg, capsules met verlengde afgifte, hard · Diltiazem HCl Sandoz retard 300 mg, capsules met verlengde afgifte, hard 
Diltiazem · Diltiazem Retard EG 200 mg g?l. lib. prol. · Diltiazem Retard EG 300 mg g?l. lib. prol. · Progor · Progor 120 mg g?l. lib. prol. · Progor 180 mg g?l. lib. prol. · Progor 240 mg g?l. lib. prol. · Progor 300 mg g?l. lib. prol. · Progor 360 mg g?l. lib. prol. · Tildiem · Tildiem 60 mg comp. · Tildiem Retard 200 mg g?l. lib. prol. · Tildiem Retard 300 mg g?l. lib. prol. 
Angiodrox · ANGIODROX 120 mg CAPSULAS DURAS DE LIBERACION PROLONGADA · ANGIODROX 180 mg CAPSULAS DURAS DE LIBERACION PROLONGADA · ANGIODROX 300 mg CAPSULAS DURAS DE LIBERACION PROLONGADA · CARRELDON RETARD 240 mg COMPRIMIDOS DE LIBERACION PROLONGADA · Cronodine · CRONODINE 120 mg CAPSULAS DE LIBERACION PROLONGADA · Diltiazem · DILTIAZEM ALTER 60 mg COMPRIMIDOS EFG · DILTIAZEM ARISTO 60 mg COMPRIMIDOS EFG · Diltiazem Dermogen 200 mg Capsulas Duras de Liberacion Prolongada efg · Diltiazem Dermogen 300 mg Capsulas Duras de Liberacion Prolongada efg · Diltiazem Farmalider 200 mg Capsulas Duras de Liberacion Prolongada efg · Diltiazem Farmalider 300 mg Capsulas Duras de Liberacion Prolongada efg · DILTIAZEM PENSA 60 mg COMPRIMIDOS EFG · Diltiazem Retard Stada 200 mg Capsulas Duras de Liberacion Prolongada efg · Diltiazem Retard Stada 300 mg Capsulas Duras de Liberacion Prolongada efg · DILTIAZEM STADA 60 mg COMPRIMIDOS EFG · Diltiwas · Diltiwas Retard 120 mg c?Psulas Duras de Liberaci?n Prolongada · Dinisor · Doclis · Doclis Retard 120 mg c?Psulas Duras de Liberaci?n Prolongada · Lacerol · Lacerol 60 mg Comprimidos · LACEROL COR RETARD 240 mg COMPRIMIDOS DE LIBERACION PROLONGADA · LACEROL HTA RETARD 240 mg CAPSULAS DURAS DE LIBERACION PROLONGADA · LACEROL RETARD 120 mg CAPSULAS DURAS DE LIBERACION PROLONGADA · LACEROL RETARD 300 mg CAPSULAS · LACEROL RETARD 90 mg CAPSULAS DURAS DE LIBERACION PROLONGADA · MASDIL 300 mg CAPSULAS DE LIBERACION PROLONGADA · MASDIL 60mg COMPRIMIDOS · MASDIL RETARD 120 mg COMPRIMIDOS DE LIBERACION PROLONGADA · Tilker · TILKER 120 mg COMPRIMIDOS DE LIBERACION PROLONGADA · TILKER 200 mg, CAPSULAS DURAS DE LIBERACION PROLONGADA · Tilker Capsulas · TRUMSAL 180 mg CAPSULAS DE LIBERACION PROLONGADA · UNI-MASDIL 200 mg CAPSULAS DE LIBERACION PROLONGADA 
Altiazem · Diladel · Diltiazem · Dilzene · Tildiem 
DILTIAZEM ARENA 60 mg · DILTIAZEM EIPICO 60 mg · DILTIAZEM LPH 60 mg · DILTIAZEM SR ROMPHARM 180 mg 
Adizem-SR · Adizem-XL · Angiozem · Angiozem CR · Angitil SR 120 · Angitil SR 180 · Angitil SR 90 · Angitil XL 240 · Angitil XL 300 · Bi-Carzem SR · Bi-Carzem XL · Calcicard CR · Dilcardia SR · Diltiazem · Dilzem SR 120 · Dilzem SR 60 · Dilzem SR 90 · Dilzem XL 120 · Dilzem XL 180 · Dilzem XL 240 · Disogram SR · Horizem SR · Kenzem SR · Optil · Retalzem 60 · Slozem · Tildiem · Tildiem LA · Tildiem LA 200 · Tildiem LA 300 · Tildiem Retard · Uard · Uard 120XL · Viazem XL · Zempt · Zemret 180 XL · Zemret 240 XL · Zemret 300 XL · Zemtard 120 XL · Zemtard 180 XL · Zemtard 240 XL · Zemtard 300 XL · Zeyam · Zildil · Zildil SR 
Cardil 
Diltiazem · Diltiazem ethypharm · Diltiazem-ratiopharm · Dilzem retard 
Dilzem 120 retard · Dilzem 180 retard · Dilzem retard · Oxycardil 120 · Oxycardil 60 
Diltiazem Retard 300mg · Diltiazem Retard EG 200mg · Progor · Tildiem · Tildiem Retard 
Cardil 
Dilzem 
Diltiazem Lannacher 
Cortiazem retard® · Diltiazem Alkaloid®
© NAPOS 2025