D01AC01 - Clotrimazole

Probably Not Porphyrinogenic

Rationale

Potent inducer of CYP3A4. Inducer of CYPs 2C8, 2C9. No significant systemic exposure in dermatological use.

Chemical description

Broadspectrum imidazole antimycotic creme 1% or cutaneous solution 1% for dermatological use in thin application Inhibitor of CYPs 11B1, 17, 19 (aromatase), 1A2, 2A6, 2C19 (potent), 2C8 (potent), 2D6. Potent CYP-inducer. No systemic effects even in long term treatment.

Ipnet drug reports

Uneventful use reported in 1 patient with acute porphyria.

Similar drugs

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D01A ANTIFUNGALS FOR TOPICAL USE
D01AC Imidazole and Triazole Derivatives

References

Tradenames

Show more details and information about the listed tradenames

Canesten · Clotrimazol

Canestene · Canestene Intim

Canespie Clotrimazol · Canesten · Clotrimazol

Candibene · Canesten · Imamono

Antimicotico · Canesten · Cangil · Clotrimazolo · Lenil Antimicotico · Lenirit Micosi

Canesten · Clotrimazol

Canesten · Corisol · Fungotox · Gromazol · Imazol

Abtrim · Boots Antifungal · Boots Pharmacy Thrush · Candiden · Canesten · Canesten AF Dual Action · Canesten Antifungal · Canesten Athlete's Foot · Canesten Dermatological · Clotrimazole · Fungederm · Galpharm Athletes Foot Cream · Galpharm Thrush Relief · Lloydspharmacy Antifungal · Lloydspharmacy Athletes Foot · Lloydspharmacy Thrush Femme

Canesten

Antifungol · Apocanda · Canesten · Klotrimazol

Canesten · Cloderm

Canesten · Clotrimazolum · Fungotac · Imazol · Imazol plus

Alibiogyn · Amicozol · Biocotryl · Canesten · Clomazol · Cloritimicotin · Clortrizol · Clotrimazol · Clotritop · Clotrizin · Creminem · Cutamycon · Epicort · Gynocanesten · Gynosten Ultra · Hongotrin · Medizol · Miclotrin · Micosan · Nimásbx · Pitoxskin