Monograph
D01AE15 - Terbinafine |
Propably not porphyrinogenic |
PNP |
Rationale
Terbinafine (ATC code: D01A E15) for topical application is classified as Probably not porphyrinogenic because of minimal systemic exposure.
For more details of the metabolism of terbinafine please refer to the monograph of terbinafine for systemic use (ATC code: D01B A02).
Hepatic exposure
Negligible
Metabolism and pharmacokinetics
Less than 5% of the dose is absorbed after topical application and systemic effect is therefore very limited (SPC).
IPNet drug reports
Uneventful use reported in 6 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Summary of Product Characteristics | |
| 1. | Norwegian medicines agency. Summary of Product Characteristics (SPC). terbinafin.
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Tradenames
Binanidda · Lamisil · Niddafin · Terbinafine 
Lamisil · Terbinafine 
Exotafin · Lamicosil · Lamisil · Scholmed · Terbinafina 
Exoterbyn · Lamisil · Terbinafin · Terbisil 
Exoterfyn · Fungisil · Lamisil · Lamiter · Taficen · Terbinafina 
Fung-X · Lamisil · Terbinafin 
Athlete Foot Cream · Lamisil · Lamisil AT · Lamisil Once · Scholl Advance Athletes Foot Cream · Terbinafine 
Finigen · Lamisil · Terbinafin · Terbistad · Terclara 
Lamisil · Terbinafin · Terbinafinhydroklorid · Terclara 
Krem przeciwgrzybiczny stóp · Lamisilatt · Myconafine · Terbiderm · Terbilum · Terbinafina · Tersilat · Undofen 
Lamisil 
Lamisil 
Fungorin · Lamisil · Lamisil Solo · Terbinafin · Terbistada · Terclara 
Exoterfyn · Lamisil · Myconafine · Posamyk · Terbinafin · Terbinafine · Terbisil · Terbital 
Exotafin · Lamisil · Terbinafin · Terbital 
Exotafin · Lamisil · Terbinafin · Terbinafine · Terbital 
Lamisil · Mycofin 
Atifan · Exoter · Lamisil · Terbinafin