Monograph
D07AC03 - Desoximetasone |
Not porphyrinogenic |
NP |
Rationale
Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
Strong glucocorticoid, creme 0.25% used in dermatology. Risk for systemic exposure in application on large areas of the skin. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.
Similar drugs
Tradenames and packages
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Netherlands
United Kingdom
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