Monograph

D07XA01 - Hydrocortisone

Not porphyrinogenic

Rationale

Hydrocortisone: Ligand to PXR. Substrate for CYPs 3A4, 3A7, 11 B2. Inducer and inhibitor of CYP 3A4. Several references stating non-porphyrinogenicity. urea: probably not absorbed.

Chemical description

Mild glucocorticoid in combination with the waterbinding agent carbamide. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncanâ€™s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.

IPNet drug reports

Uneventful use reported in 3 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes D07X / D07XA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Miconazolnitraat / Hydrocortison · Miconazolnitraat/Hydrocortison Aurobindo 20/10 mg/g, hydrofiele crème · Pimafucort · Pimafucort, gel, 10 mg/g, 10 mg/g, 3,5 mg/g

United Kingdom

Alphaderm · Alphaderm 1%/10% cream · Calmurid HC · Calmurid HC cream · Coal tar / Hydrocortisone · Coal tar 10% in Hydrocortisone 1% cream · Coal tar solution 12% / Salicylic acid 2% in Hydrocortisone 1% ointment · Eurax Hc · Eurax Hc cream · Eurax Hydrocortisone · Eurax Hydrocortisone cream · Hydrocortisone / Hydroquinone · Hydrocortisone 1% / Hydroquinone 4% in Aqueous cream · Hydrocortisone 1% / Tretinoin 0.025% / Hydroquinone 4% in Aqueous cream · Hydrocortisone 1% / Tretinoin 0.025% / Hydroquinone 4% in Unguentum M cream · Hydrocortisone 1% / Tretinoin 0.1% / Hydroquinone 5% cream · Hydrocortisone 1% / Tretinoin 0.1% / Hydroquinone 5% cutaneous solution · Hydrocortisone 2.5% / Tretinoin 0.1% / Hydroquinone 5% cream · Hydrocortisone / Salicylic acid · Hydrocortisone 0.5% / Salicylic acid 0.25% in Aqueous cream · Hydrocortisone / Sulfur · Hydrocortisone 1% / Salicylic acid 1% / Sulfur 1% in Aqueous cream · Hydrocortisone 1% / Salicylic acid 1% / Sulfur 1% in Unguentum M cream · Hydrocortisone 2.5% / Sulfur 1% in Aqueous cream · Hydromol HC · Hydromol HC Intensive cream · Nystaform HC · Nystaform HC cream · Nystatin · Nystatin 100,000units/g / Chlorhexidine hydrochloride 1% / Hydrocortisone 0.5% cream

Finland

Pantyson

Acute Porphyria Drug Database

Monograph