D07XC01 - Betamethasone |
Not porphyrinogenic |
NP |
Rationale
The glucocorticoid and ASA components are stated in several references not to be porphyrinogenic. Probably only insignificant systemic exposure.
Chemical description
Strong glucocorticoid 0.5 mg/g in combination with acetylsalicylic acid. Ointment used in steroide sensitive dermatoses.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Porphyria and the dangerous life-threatening drugs.
Eales L. S Afr Med J. 1979 Nov; 56(22):914-7.
|
515871 |
| 2. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| 3. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Porphyria Drug Lists | ||
| 4. | Michael Moore's List
No longer maintained
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| 5. | South African List
Porphyria South Africa No longer maintained
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| Other sources | ||
| 6. | Porphyrin metabolism and the Porphyrias [Book Chapter]
Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.
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Tradenames