Acute Porphyria Drug Database

Monograph

G02AD02 - Dinoprostone
Propably not porphyrinogenic
PNP

Rationale
Endogenous prostaglandin. Low dose. Probably insignificant hepatic CYP metabolic load.
Chemical description
(DINOPROSTONE) Endogenous prostaglandin F2 alpha in vaginal gel (0.5- 2 mg /dose) used for cervix maturation and induction of labour. Short half life. Inactivated on passing the lungs. Metabolized by beta oxidation. Substrate for CYP 4F8. Inhibitor of CYPs 2B6 and 2C9.

Similar drugs
Explore alternative drugs in similar therapeutic classes G02A / G02AD or go back.

Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.
Netherlands
Prepidil · Prepidil 0,5 mg/3 g, gel voor endocervicaal gebruik · Propess · Propess, vaginaal toedieningssysteem 10 mg · Prostin E2 · Prostin E2, gel voor vaginaal gebruik 1 mg · Prostin E2, gel voor vaginaal gebruik 2 mg
Belgium
Prepidil · Prepidil 0.5 mg - 3 g gel endocervic. ser. préremplie · Propess · Propess 10 mg système de diffusion vagin. sachet · Prostin E2 · Prostin E2 0.5 mg comp. · Prostin E2 0.75 mg sol. perf. (à diluer) i.v. amp. · Prostin E2 1 mg gel vagin. ser. préremplie · Prostin E2 2 mg gel vagin. ser. préremplie · Prostin E2 3 mg compr. vagin. · Prostin E2 5 mg sol. perf. (à diluer) i.v. amp.
United Kingdom
Dinoprostone · Dinoprostone 10mg vaginal device · Propess · Propess 10mg vaginal delivery system · Prostin E2 · Prostin E2 1mg vaginal gel · Prostin E2 2mg vaginal gel · Prostin E2 3mg vaginal tablets · Prostin E2 5mg/0.5ml extraamniotic solution ampoules · Prostin E2 5mg/0.5ml solution for infusion ampoules · Prostin E2 750micrograms/0.75ml solution for infusion ampoules
Denmark
Minprostin · Propess
Norway
Minprostin · Propess · Prostin E2
Poland
Cervidil · Prepidil
Luxembourg
PREPIDIL · PROPESS · PROSTIN E2
Finland
Propess
Latvia
Propess · Prostenoon-Geel
Serbia
Prepidil · Prepidil® · PROPESS · PROPESS® · Prostin · Prostin® E2
 
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