G04CA03 - Terazosin |
Probably not porphyrinogenic |
PNP |
Rationale
No data pointing to CYP-interaction. Two references authorised / use with care.
Chemical description
Used in hypertrophic prostatic disease, 2-5 mg/d. Quinazoline derivative with selective effect on alpha-1-receptors in the bladder, giving rise to relaxation. Metabolized in the liver by hydrolysis and demethylation. No data pointing to CYP-interaction.
IPNet drug reports
Uneventful use reported in 3 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | French List
Centre Français des Porphyries
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| 2. | South African List
Porphyria South Africa No longer maintained
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Tradenames