G04CB01 - Finasteride

Possibly porphyrinogenic

Rationale

Substrate for CYP3A4. Conflicting evidence of porphyrinogenicity.

Chemical description

A 4-azasteroide used in prostatic hypertrophy, 5 mg/d. Competitive inhibitor of 5-alpha reductase which converts testosterone to the more potent androgen dihydroform needed for the growth of the prostatic tissue. Metabolized by CYP3A4.

IPNet drug reports

Uneventful use reported in 3 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes G04C / G04CB or go back.

References

#	Citation details	PubMed ID
Porphyria Drug Lists
1.	French List Centre Français des Porphyries
2.	South African List Porphyria South Africa No longer maintained

Tradenames

Show more details and information about the listed tradenames

Finasteride · Proscar

Chibro-Proscar · Finasteride

Arahormo · Finasterida · Litace · Normomale · Proscar

Finanorm · Finasterid · Finasteride · Finpros · Prosterid · Redupros

Asterid · Finasteride · Finastid · Finedor · Finestar · Genaprost · Ormicton · Proscar · Prostide · Ridestin · Sitas · Stecur · Terip

Finasterida · Proscar

Finasterax · Finasterid · Proscar

Finasteride · Proscar

Finasterid · Finasteride

Finasterid · Finasteride · Finpros · Proscar

Finamed · Finasterid · Proscar

Adaster · Androster · Antiprost · Apo-Fina · Finahit · Finamef · Finaran · Finaride · Finaster · Finasterid · Finasteride · Finasteridum · Finpros · Finxta · Hyplafin · Penester · Proscar · Symasteride · Uronezyr · Zasterid