J01CE02 - Phenoxymethylpenicillin |
Not porphyrinogenic |
NP |
Rationale
Water-soluble lactam type penicillin. Considerable clinical experience as well as references point to non-porphyrinogenicity.
Chemical description
Penicillinase susceptible penicillin used perorally (0.8 - 1.0 g x 2). Water-soluble antibiotic of betalactam type. Mainly excreted in urine where 30-50% of the dose is found in active form within 8 hours.
Personal communication
Thunell, patient inquiry: well tolerated (n=4).
Andersson: Used in several patients without side effects.
IPNet drug reports
Uneventful use reported in 48 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Acipen-V · Fenoxymethylpenicilline 
Oracilline · Phenoxymeth.ucp 
Penilevel 
Ospen 
Ospen 
Ospen 
Phenoxymethylpenicillin · Tenkicin 
Fenoximetylpenicillin · Ospen · Pancillin · PenHEXAL · Phenoxymethylpenicillin · Phenoxymethylpenicillinkalium · Primcillin · Priminova · Primve 
Avopenin · Fenoximetylpenicillin · Fenoxymethylpenicilline · Kåvepenin · Peceve · PenHEXAL · Penicillin Potassium · Penon · Phenoxymethylpenicillin · Primve · Tikacillin 
Actacillin · Apocillin · Fenoxymethylpenicilline · Ospen · Pancillin · Penon · Phenoxymethylpenicillin · Weifapenin 
Ospen · Polcylin 
Penviotina 
Cilicaine VK · Compocillin VK · mil-vk · Penicillin · Penicillin VK · Phenoxymethylpenicillin · Rocilin 
Penopen 
pen-vk 
Fenoximetylpenicillin · Kåvepenin 
V-Pen 
Ospen · Phenoxymethylpenicillin · v-Penicilin · v-pnc 
Ospen 
Ospen · Vepicombin 
Largocilin · Ospen 
Ospen · Penon · Silapen K 
Ibaden · Kalijev fenoksimetilpenicilinat · Ospen · Penicillin 
Ospen · Penbene · Phenoxymethylpenicillin · v pnc · v-Penicilin