J01CR05 - Piperacillin and Beta-Lactamase Inhibitor |
Probably not porphyrinogenic |
PNP |
Rationale
Piperacillin: Not metabolized. Two references consider it safe.
Tazobactam: Mainly excreted in unchanged form.
Chemical description
Piperacillin: Broadspectrum penicillin used parenterally (4g x 3) in septicemia where Pseudomonas infection is verified or suspected. Excreted in bile and by the kidneys in unchanged form. No data pointing to CYP interaction. Tazobactam: Betalactamase inhibitor (up to 500 mg/24 h) mainly excreted via the kidneys in unchanged form.
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | EPI List
European Porphyria Initiative No longer maintained
|
|
| 2. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Piperacillin / Tazobactam · Pitaz 
Piperacillin / Tazobactam · Tazocin 
Piperacillin / Tazobactam · Tazocilline 
Piperacillin / Tazobactam · Pitaz 
Piperacillin / Tazobactam 
Ibitazina · Limerik · Piperacillin / Tazobactam · Taiper · Tazocin · Tazopenil · Textazo 
Perasin · Piperacillin / Tazobactam · Pitaz 
Piperacillin / Tazobactam · Tazobac 
Piperacillin / Tazobactam · Tazocin 
Piperacillin / Tazobactam · Tazocin 
Extempore J01CR05 Piperacillin enzymhämmare · Piperacillin / Tazobactam · Pipitaz · Tazocin · Tazopenil 
Pip/Taz · Piperacillin / Tazobactam 
Piperacillin / Tazobactam · Tazocin 
Aurotaz-p · Delbactam · Kabictam · Penibectam · Piperacillin / Tazobactam · Salataz · Sumimed Pipertazo · Tapectam · Tazocin · Tazodelt 
Piperacillin / Tazobactam · PiperTaz · Pipetam · PipTaz · Tazocin · Tazocin EF · Zobacin 
Piperacillin / Tazobactam · Piptaz · Salataz · Tazocin · Tazpen 
Piperacillin / Tazobactam 
Piperacillin / Tazobactam · Tazocin 
Piperacillin / Tazobactam 
Piperacillin / Tazobactam 
Eratia · Perasin · Piperacillin / Tazobactam · Tazocin 
Eratia · Piperacillin / Tazobactam 
Eriz · Piperacillin / Tazobactam · Tazocin 
Perasin · Piperacillin / Tazobactam · Piptaz · Tavoctame 
Acipirin · Piperacillin / Tazobactam · Pitaz · Tazoprox 
Piperacillin / Tazobactam · Tazocin 
Apiz · Kezutin · Piperacillin / Tazobactam · Refocil · Tazip 
Zosyn