J01DC02 - Cefuroxime
Probably Not Porphyrinogenic
PNP
Rationale
Conflicting references. Not metabolised. No data pointing to CYP-interaction. Some clinical experience of non-porphyrinogenicity.
Chemical description
Parenteral cephalosporin antibiotic used (up to 1.5g x 3) e.g. in bacterial pneumonia, upper urinary tract infection and several other conditions. Not significantly metabolised. Mainly excreted in unchanged form in urine. No data pointing to CYP affinity.
Personal communication
Andersson: Used a few times without side effects.
Ipnet drug reports
Uneventful use reported in 10 patients with acute porphyria.
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J01D OTHER BETA-LACTAM ANTIBACTERIALSJ01DC Second-Generation CephalosporinsReferences
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Citation details
PubMed ID
1.
Australian List
Australian Porphyria Association No longer maintained
2.
French List
Centre Français des Porphyries
3.
South African List
Porphyria South Africa No longer maintained
Tradenames
Show more details and information about the listed tradenames
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