Acute Porphyria Drug Database

Monograph

J01DB05 - Cefadroxil
Propably not porphyrinogenic
PNP

Rationale
Not metabolised. No data pointing to CYP interaction. Conflicting references.
Chemical description
Perorally used cephalosporin (500 mg x 2) antibiotic used in uncomplicated urinary tract infections, skin and soft tissue infections and in pharyngotonsillitis where penicillin V has shown to be without effect. Only about 2 % is metabolized by decarbamylation, the drug thus mainly excreted in unchanged form by the kidneys. No data pointing to CYP-affinity. South African list: use with caution . French list: unsafe. Andersson:used occasionally without side effects.Said by one patient, however, to have triggered symtoms.
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.

Similar drugs
Explore alternative drugs in similar therapeutic classes J01D / J01DB or go back.

Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.
Belgium
Cefadroxil · Cefadroxil Sandoz 500 mg gél. · Duracef · Duracef 250 mg/5 ml susp. buv. (pdr.) · Duracef 500 mg/5 ml susp. buv. (pdr.)
United Kingdom
Baxan · Baxan 125mg/5ml oral suspension · Baxan 250mg/5ml oral suspension · Baxan 500mg capsules · Baxan 500mg/5ml oral suspension · Cefadroxil · Cefadroxil 500mg capsules
Poland
Duracef · Valdocef
Luxembourg
DURACEF
Latvia
Biodroxil · Duracef
Serbia
VALDOCEF · VALDOCEF®
 
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