J01DD01 - Cefotaxime |
Probably not porphyrinogenic |
PNP |
Rationale
Metabolised only to a limited extent. No data pointing to CYP-interaction. Two references consider the drug safe.
Chemical description
Parenteral betalactamase stable cephalosporin used (1g x 2) in various infections. Excreted in unchanged form (50-60%), and as desacetyl derivative 15-25%, by the kidneys within 24 hours. No data pointing to CYP interactions,
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | French List
Centre Français des Porphyries
|
|
| 2. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Cefotaxim 
Cefotaxime · Claforan 
Cefotaxima · Valoran 
Cefotaxim · Cefotaxime 
Batixim · Cefotaxima · Cefotaxime · Salocef · Spectrocef · Taxime · Zariviz · Zimanel 
Cefotax · Cefotaxim · Cefotaxima 
Cefotaxime · Claforan 
Cefotaxim 
Cefotaxim · Cefotaxima · Cefotaxime Sodium · Claforan · Extempore J01DD01 Cefotaxim 
Cefotaxim 
Biotaksym · Cefotaxim · Cefotaxime · Tarcefoksym 
Cefotaxima 
Cefotaxime 
Cytaxin 
Cefotaxime Sodium 
Cefotaxime · Claforan 
Cefotaxim 
Cefotaxim 
Biotaksym · Cefotax · Cefotaxim · Cefotaxime · Moxicef · Stoparen 
Cefotaxime · Valoran 
Cefotaxime · Valoran 
Cefotaxim 
Cefotaksim 
Altacef · Cefotaksim · Cefotaxim · Cefotaxima · Claforan · Makrocef · Valoran 
Cefotaxime · Sefotak · Taximed 
Cefotaxima 
Cefotaxime