Probably not significantly metabolised. Conflicting references.

Perorally administered cephalosporin (200mg x 2) used in pharyngotonsillitis, otitis media and sinusitis where treatment with penicillins have shown to be without effect. About 20% of an oral dose (or 50% of the absorbed dose) is excreted unchanged in urine within 24 hours. Up to 60% may be eliminated by non-renal mechanisms. There is no evidence of metabolism but some of the drug is probabably excreted via bile.

Uneventful use reported in 2 patients with acute porphyria.