Monograph
J01FA10 - Azithromycin |
Propably not porphyrinogenic |
PNP |
Rationale
Low potency inhibitor of CYP3A4, probably only poorly interfering with the CYP system. Mechanism based inhibition less likely. Conflicting references.
Chemical description
Macrolide antibiotic used (500-250 mg /d) in urogenital infections caused by Clamydia and in gonococcal genital infections. Only small amounts metabolized in the liver by demethylation. Low potency inhibitor of CYP3A4. South African list: use with extreme caution only. French list: can be used.
IPNet drug reports
Uneventful use reported in 13 patients with acute porphyria.
Similar drugs
Tradenames and packages
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Netherlands
Azitromycine · Azitromycine 200 mg/5 ml Teva, poeder voor orale suspensie · Azitromycine 200 mg/5 ml, poeder voor orale suspensie · Azitromycine 250 mg Teva, filmomhulde tabletten · Azitromycine 500 mg Teva, filmomhulde tabletten · Azitromycine Aurobindo 250 mg, filmomhulde tabletten · Azitromycine Aurobindo 500 mg, filmomhulde tabletten · Azitromycine CF 200 mg/5 ml, poeder voor orale suspensie · Azitromycine CF 250 mg, filmomhulde tabletten · Azitromycine CF 500 mg, filmomhulde tabletten · Azitromycine Eberth 500 mg, poeder voor concentraat voor oplossing voor infusie · Azitromycine Jubilant 250 mg filmomhulde tabletten · Azitromycine Jubilant 500 mg filmomhulde tabletten · Azitromycine Mylan 100 mg/5 ml, poeder voor orale suspensie · Azitromycine Mylan 200 mg/5 ml, poeder voor orale suspensie · Azitromycine ratiopharm 250 mg, filmomhulde tabletten · Azitromycine ratiopharm 500 mg, filmomhulde tabletten · Azitromycine Sandoz 100 mg/5 ml, poeder voor orale suspensie · Azitromycine Sandoz 200 mg/5 ml, poeder voor orale suspensie · Azitromycine Sandoz 250 mg, filmomhulde tabletten · Azitromycine Sandoz 500 mg, filmomhulde tabletten · Azitromycine Viatris 250 mg, filmomhulde tabletten · Azitromycine Viatris 500 mg, filmomhulde tabletten · Zithromax · Zithromax 250, tabletten 250 mg · Zithromax 500, tabletten 500 mg · Zithromax, suspensie (poeder voor) 200 mg/5 mlBelgium
Azithromycin · Azithromycin AB 250 mg compr. pellic. · Azithromycin AB 500 mg compr. pellic. · Azithromycine · Azithromycine EG 200 mg/5 ml susp. buv. (pdr.) · Azithromycine EG 250 mg compr. pellic. · Azithromycine EG 500 mg compr. pellic. · Azithromycine Sandoz 200 mg/5 ml susp. buv. (pdr.) · Azithromycine Sandoz 250 mg compr. pellic. · Azithromycine Sandoz 500 mg compr. pellic. · Azithromycine Teva 250 mg compr. pellic. · Azithromycine Teva 500 mg compr. pellic. · Zitromax · Zitromax 200 mg/5 ml susp. buv. (pdr.) · Zitromax 250 mg compr. pellic. · Zitromax 500 mg compr. pellic. · Zitromax 500 mg sol. perf. (pdr., à diluer) i.v. flac. · Zitromax 600 mg compr. pellic.United Kingdom
Azithromycin · Azithromycin 200mg/5ml oral suspension · Azithromycin 200mg/5ml oral suspension sugar free · Azithromycin 250mg capsules · Azithromycin 250mg tablets · Azithromycin 500mg powder for concentrate for solution for infusion vials · Azithromycin 500mg tablets · Azitromax · Azitromax 500mg powder for solution for injection vials · Clamelle · Clamelle 500mg tablets · Zedbac · Zedbac 500mg powder for solution for infusion vials · Zithromax · Zithromax 200mg/5ml oral suspension · Zithromax 250mg capsules · Zithromax 500mg tabletsDenmark
Amzolynic · Azithromycin · Azithromycin "2care4" · Azithromycin "Epione Medicine" · Azithromycin "Jubilant" · Azithromycin "Krka" · Azithromycin "Mylan" · Azithromycin "Nordic Prime" · Azithromycin "Orifarm" · Azithromycin "Sandoz" · Azithromycin "Stada" · Azithromycin "Teva" · Azithromycin Sandoz · Azithromycin Teva · Zithromax · ZitromaxNorway
Amzolynic · Azithromycin hexal · Azitromax · Azitromicina Qualigen · ZithromaxPoland
Abiazyt · Azibiot · Azimycin · Azithromycin Aurovitas · Azithromycin Genoptim · Azithromycin Krka · Azithromycin Teva · Azithromycin ZIM · AzitroLEK · AzitroLEK 250 · AzitroLEK 500 · Azitrox 500 · Azycyna · Bactrazol · Macromax · Nobaxin · Sumamed · Sumamed forteLuxembourg
Azithromycin · Azithromycin Dr. Friedrich Eberth · Azithromycin-ratiopharm · AZITHROMYCINE · AZITHROMYCINE EG · AZITHROMYCINE EG-500 · ZITROMAXIceland
Azithromycin · Azithromycin Eberth · Azithromycin STADA · Azitromicina · Azitromicina Normon · ZitromaxFinland
Amzolynic · Azithromycin Krka · Azithromycin Orion · Azithromycin Ratiopharm · Azithromycin Sandoz · Azithromycin STADA · Zithromax · Zithromax IVLatvia
Azibiot · Azithromycin · Azithromycin Sandoz · SumamedSerbia
Azibiot · Azibiot® · Azinocin · Azinocin® · Hemomycin · Hemomycin® · Sumamed · Sumamed® kapsule · Sumamed® tablete 500
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