J01GB03 - Gentamicin |
Not porphyrinogenic |
NP |
Rationale
Aminoglycoside, not metabolised. Three references state non-porphyrinogenicity.
Chemical description
Broadspectrum aminoglycoside antibiotic. Eliminated in unchanged form by glomerular filtration.
IPNet drug reports
One very well documented report of an attack requiring hospitalisation and treatment with heme arginate in a 39 year old susceptible female with AIP. However the patient also had an infection with fever that just as well could have caused the attack. Uneventful use reported in 4 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | South African List
Porphyria South Africa No longer maintained
|
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Tradenames
Garacol · Gentamicine 
Duracoll · Gentamycine 
Gentamicine pan 
Genta · Gentamicina 
Gentamicin 
Gentamicina · Gentamicina Solfato 
Gentamicin · Gentamicina 
Garamycin · Gentamicin 
Cidomycin · Cidomycin Intrathecal · Cidomycin Paediatric · Gentamicin · Gentamicin Intrathecal · Gentamicin Paediatric · Gentamicin Redibag · Genticin Injectable · Septopal Chain (10 beads) · Septopal Chain (30 beads) · Septopal Minichain (10 beads) 
Gentacoll · Gentamicin · Hexamycin 
Extempore J01GB03 Gentamicin · Garamycin · Gensumycin · Genta · Gentacoll · Gentamicin · Gentamicine · Refobacin · Septopal 
Gensumycin · Gentamicin 
Garamycin · Gentamicin · Gentamycin 
Biogenta · Gentamicina 
Garamycin · Gentamicin · Gentamicin Sulphate · Gentamycin 
Garasent · Gentamicin · Miramycin 
Gentamicin · Gentamicin(e) 
Duracoll · Gentamicin 
Gentacoll · Gentamicin 
Gensumycin · Gentacoll 
Gentamicin · Gentamicina 
Gentamicin 
Gentamicin 
Gentamicin 
Garamycin · Gentamicin 
Garamycin · Gentamicin · Septopal 
Garamycin · Gentamicin