J01XC01 - Fusidic Acid |
Not porphyrinogenic |
NP |
Rationale
Hydrophilic steroid structure. May act as a CYP inducer on prolonged (> 2 weeks) use. Several references: safe/use
Chemical description
Antibacterial steroid used in staphylococcal infections. Excreted in bile after oxidative metabolism and glucuronidation. CYP-induction demonstrated not after 14 days, but after one month of therapy.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | Australian List
Australian Porphyria Association No longer maintained
|
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| 2. | French List
Centre Français des Porphyries
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| 3. | South African List
Porphyria South Africa No longer maintained
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Tradenames