J01XE01 - Nitrofurantoin |
Porphyrinogenic |
P |
Rationale
Hydantoin derivative. Associated with attacks. Several references warn against it.
Chemical description
Nitrofuran derivative used in urinary tract infections. Between 30% and 50% of the dose is excreted in urine in unchanged form. No further data on metabolism or CYP interaction.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Drug reference publications | ||
| 2. | Martindale: The complete drug reference. Pharmaceutical Press.
Sweetman SC, editor.
|
|
| Porphyria Drug Lists | ||
| 3. | Australian List
Australian Porphyria Association No longer maintained
|
|
| 4. | South African List
Porphyria South Africa No longer maintained
|
|
| Other sources | ||
| 5. | Porphyrin metabolism and the Porphyrias [Book Chapter]
Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.
|
|
Tradenames
Foragen · Furabid · Furadantine · Nitrofurantoine · Nitrofurantoïne 
Furadantine · Nitrofurantoin 
Furadantine 
Furantoina 
Nitrofurantoin · Nitrofurantoin-Chinoin · Nitrofurantoin-q 
Furecis · Furedan · neo Furadantin · Nitrofurantoina 
Furolin · Nitrofurantoina 
Furadantin · Nitrofurantoin · Uvamin 
Furadantin · Genfura · Macrobid · Macrodantin · Nitrofurantoin · Urantoin 
Foragen · Nitrofurantoin 
Furadantin · Nitrofurantoin 
Furadantin · Furadantine · Furantoina · Nifurantin · Nitrofurantoine 
Diviaren · Furantomed · Nitrofurantoina 
Furadantin · Macrobid · Macrodantin · Nifuran · Nitrofurantoin 
Nitrofurantoin 
Nitrofurantoin 
Furadantine 
Furadantin 
Foragen · Furantoina · Furuti · Nitrofur-C 
Furabid · Furadonins · Magromag · Uvamin 
Furadonins · Magromag · Nitrofurantoin · Uvamin 
Magromag · Nitrofurantoin 
Funitral · Nitrofinn · Nitrurix 
Ninur · Nitrofurantoin · Prevuro 
Furadantin · Furadantine · Macrobid · Macrodantin · Ninur · Nitrofurantoin · Nitrofuration 
Furolin · Nitrofurantoin · Nostiriazyn