Monograph
J05AF08 - Adefovir Dipivoxil |
Propably not porphyrinogenic |
PNP |
Rationale
Probably no significant CYP-interactions.
Chemical description
Oral prodrug to adefovir that is an acyclic nucleotide phosphonate analogue, which intracellularly is converted to adefovir diphosphate, inibitor of viral polymerases. Used, tabl 10 mg/d, in the treatment of chronic hepatitis B in adults with signs of liver engagement. The risk for CYP related drug interactions is considered low.
Similar drugs
Tradenames and packages
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