A06AB02 - Bisacodyl |
Probably not porphyrinogenic |
PNP |
Rationale
Probably insignificant systemic exposure.
Chemical description
Contact laxative. Enterotablets 5-10 mg/d or suppositories 10 mg/d. Diphenyl pyridine derivative hydrolyzed in the intestine to desaetylbisacodyl, which is absorbed and excreted in urine and bile as glucuronide. A diphenol is formed in colon which stimulates motility. Only minute amounts reach the systemic circulation.
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Bisacodyl · Dulcolax 
Bisacodyl · Dulcolax · Purgo-Pil 
Bekunis · Dulcolax 
Dulcolax · Laxamed · Stadalax 
Alaxa · Confetto · Dulcolax · Lovoldyl · Normalene · Stixenil · Verecolene 
Bisacodil · Dulcolax · Laxamag · Stadalax 
Bekunis Bisacodyl · Bisacodyl · Bisacodyl-N · Bisacofelan · Dulcolax · Medibudget Abführdragées Bisacodyl · Muxol · Prontolax · Tavolax 
Bisacodyl · Boots Constipation Relief · Dulcolax · Dulcolax Adult · Dulcolax Twelve Plus · Entrolax · Galpharm Constipation Relief · Numark Constipation Relief · Vantage Pharmacy Constipation Relief 
Dulcolax · Toilax 
Dulcolax · Toilax 
Dulcolax · Toilax 
Bisacodyl · Dulcobis 
Bisacodilo · Bisalax · Dulcolax · Farmalax · Izocol · Laxium · Lerlez · Nadylax 
Bisacodyl · Bisalax · Dulcolax · Fleet · Lax-Suppositories Bisacodyl · Lax-Tab · Neo Bisacodyl 
Biolax · Bisacodyl · Dilax · Dulcolax · Laxodyl · s.l. · Sunny · Unilax 
Bisacodyl · Bisacodyl-Odan · Carter's Little · Codulax · Dulcolax · Laxative · Silver Bullet · the Magic Bullet 
Dulcolax · Purgo-pil 
Dulcolax · Toilax 
Toilax 
Bisacodyl 
Bisacodyl 
Bisacodyl 
Dulcolax · Panlax 
Dulcolax · Novolax 
Bisacodyl · Bisacodyl-k · Dulcolax · Fenolax · Stadalax