Monograph
J07BC02 - Hepatitis A, Inactivated, Whole Virus |
Propably not porphyrinogenic |
PNP |
Rationale
Based on the pharmacokinetics of the hepatitis A, inactivated, whole virus vaccine, there are no conceivable porphyrinogenic effects.
Chemical description
Inactivated hepatitis A virus.
Therapeutic characteristics
The vaccine is indicated for the active immunization of adults and children over the age of 1against hepatitis A. It is administered by a single intramuscular injection. A booster dose is recommended after 6-12 months in order to obtain more persistent immunity.
Metabolism and pharmacokinetics
The hepatitis vaccine is not metabolized by the cytochrome P450 system.
IPNet drug reports
Uneventful use reported in 5 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Government bodies | |
| 1. | Norwegian Institute of Public Health. Vaksinasjonsveilederen. www.fhi.no (updated 13.10.2015).
|
|
| * | Summary of Product Characteristics | |
| 2. | The electronic Medicines Compendium (emc). Summary of Product Characteristics (SPC). Havrix.
|
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Tradenames
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Avaxim, suspensie voor injectie in een voorgevulde spuit 160U/0,5 ml · Havrix 1440, suspensie voor injectie · Havrix Junior, suspensie voor injectie · Vaqta Adult, suspensie voor injectie 50 E/ml · Vaqta Junior, suspensie voor injectie 25 E/0,5 ml 
Avaxim · Avaxim 0.5 ml susp. inj. s.c./i.m. ser. pr?remplie · Havrix · Havrix 1440 susp. inj. s.c./i.m. flac. · Havrix 1440 susp. inj. s.c./i.m. ser. pr?remplie · Havrix Junior 720 susp. inj. s.c./i.m. flac. · Havrix Junior 720 susp. inj. s.c./i.m. ser. pr?remplie · Vaqta · Vaqta 50 UI/ml susp. inj. s.c./i.m. ser. pr?remplie · Vaqta Junior 25 UI/0.5 ml susp. inj. s.c./i.m. flac. · Vaqta Junior 25 UI/0.5 ml susp. inj. s.c./i.m. ser. pr?remplie 
Avaxim Junior Suspension Inyectable en Jeringa Precargada · Avaxim Suspension Inyectable en Jeringa Precargada · Havrix 1440 Adulto, Suspension Inyectable en Jeringa Precargada · Havrix 720 Junior, Suspension Inyectable en Jeringa Precargada · Vaqta · VAQTA 25 UNIDADES/ 0,5 ml SUSPENSION INYECTABLE · VAQTA 50 UNIDADES/1 ml SUSPENSION INYECTABLE 
Avaxim 160 u Vaccin Hepatitic a · Avaxim 80 u Pediatric, Vaccin Hepatitic a · Havrix Adult 1440 Vaccin Hepatitic a · Havrix Junior 720 Vaccin Hepatitic a 
Avaxim · Avaxim vaccine · Epaxal Berna · Epaxal vaccine · Havrix · Havrix Junior Monodose vaccine · Havrix Monodose vaccine · Vaqta · VAQTA Paediatric vaccine · VAQTA vaccine 
Avaxim · Avaxim Junior · Havrix · Vaqta 
Havrix 
Avaxim 160 U · Havrix 720 Junior · Havrix Adult · Vaqta 25 · Vaqta 50 
Avaxim · Havrix 1440 · Havrix Junior 720 · Vaqta · Vaqta Junior 
Havrix 
Avaxim · Havrix · Vaqta 
Avaxim · Havrix · Havrix 720 ELISA 
Avaxim® 160 U
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