Substrate for CYP2C9 and 3A4. One list considers it probably safe.
Chemical description
Tabl, supp, 7-15 mg/d. Analgetic, antipyretic och anti-inflammatory inhibitor of prostaglandin synthesis used in osteoarthrosis. Oxicam derivative, extensively metabolized by hydroxylation by CYP2C9 (major reaction) and 3A4 (minor reaction). Inhibitor of CYP2C9.
IPNet drug reports
Uneventful use reported in 5 patients with acute porphyria.
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