M02AA10 - Ketoprofen |
Not porphyrinogenic |
NP |
Rationale
Insignificant systemic exposure. Two references consider it (probably) safe. Did not induce ALAS1 in rat.
Chemical description
Gel 2.5%. Analgetic and antiinflammatory gel for dermal application. Bioavailability after percutaneous administration about 5%.
IPNet drug reports
Uneventful use reported in 19 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | French List
Centre Français des Porphyries
|
|
| 2. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Fastum 
Fastum 
Fastum · Keplat · Ketospray 
Artrosilene · Fastum · Flexen · Ibifen · Keplat · Ketoprofene · Orudis 
Fastum · Ketomag · Ketonal · Ketoprofen · Ketospray 
Fastum 
Ketoprofen · Oruvail · Powergel · Tiloket 
Ketoflex · Ketospray · Orudis · Siduro · Zon 
Effekton Ketoprofen · Orudis 
Fastum · Ketonal · Ketoprofen · Ketoprofenum Fastum · Ketospray Forte · Opokan-keto · Ultrafastin 
Ketoflex · Ketoprofeno · Ketum · Profenid 
Fastum · Ketum · Oruvail 
Fastum · Harufen · Kefentech · Kefentech air · Kenhancer · Ketofen · Ketotop 
Fastum 
Orudis 
Begsan · Fastum · Ketoprofen 
Begsan · Fastum 
Begsan · Fastum · Prontoflex 
Artrocol · Fastum · Ketonal 
Fastum · Ketonal 
Fastum · Ketonal · Prontoflex 
Fastum · Keplat · Ketonal · Prontoflex