M03AC01 - Pancuronium |
Probably not porphyrinogenic |
PNP |
Rationale
Non-CYP dependent metabolism. Two references consider it (probably) safe. Porphyrinogenic in rat model.
Chemical description
Aminosteroide muscle relaxant used in surgery and during orthopedic measures. Partly metabolised in the liver, partly excreted in unchanged form.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Induction of anaesthesia with etomidate in a patient with acute intermittent porphyria.
Famewo CE. Can Anaesth Soc J. 1985 Mar; 32(2):171-3.
|
3986654 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Pancuronium bromide · Pavulon 
Pancuronium · Pancuroniumbromid · Pavulon 
Pancuronium 
Pancuronium 
Bromuro Pancuronio 
Pancuronium 
Pavulon 
Pancuronium